{"id":99320,"date":"2025-08-11T10:31:11","date_gmt":"2025-08-11T07:31:11","guid":{"rendered":"https:\/\/www.lovendal.ro\/wp52\/?p=99320"},"modified":"2025-08-11T10:31:11","modified_gmt":"2025-08-11T07:31:11","slug":"500-de-ani-mai-tarziu-oamenii-de-stiinta-rezolva-misterul-inimii-umane-desenata-de-leonardo-da-vinci","status":"publish","type":"post","link":"https:\/\/www.lovendal.ro\/wp52\/500-de-ani-mai-tarziu-oamenii-de-stiinta-rezolva-misterul-inimii-umane-desenata-de-leonardo-da-vinci\/","title":{"rendered":"500 de ani mai t\u00e2rziu, oamenii de \u0219tiin\u021b\u0103 rezolv\u0103 misterul inimii umane, desenat\u0103 de Leonardo da Vinci"},"content":{"rendered":"<p><a href=\"https:\/\/www.lovendal.ro\/wp52\/wp-content\/uploads\/2025\/08\/trabeculi.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-99321\" src=\"https:\/\/www.lovendal.ro\/wp52\/wp-content\/uploads\/2025\/08\/trabeculi.jpg\" alt=\"\" width=\"357\" height=\"242\" srcset=\"https:\/\/www.lovendal.ro\/wp52\/wp-content\/uploads\/2025\/08\/trabeculi.jpg 357w, https:\/\/www.lovendal.ro\/wp52\/wp-content\/uploads\/2025\/08\/trabeculi-300x203.jpg 300w\" sizes=\"auto, (max-width: 357px) 100vw, 357px\" \/><\/a>Dup\u0103 500 de ani, cercet\u0103torii au \u00een\u021beles \u00een sf\u00e2r\u0219it func\u021bia anatomic\u0103 a unei caracteristici a inimii descrise pentru prima dat\u0103 de <strong>Leonardo da Vinci<\/strong>. Pentru a g\u0103si r\u0103spunsul, oamenii de \u0219tiin\u021b\u0103 au folosit teoria fractal\u0103, RMN-urile \u0219i mult efort computa\u021bional pentru a elucida structurile numite <strong>trabecule<\/strong>. Ei au descoperit c\u0103 acest strat muscular ramificat, ca fulgii de z\u0103pad\u0103, joac\u0103 un rol \u00een riscul bolilor de inim\u0103. <em>&#8222;Suprafe\u021bele interioare ale inimii umane sunt acoperite de o re\u021bea complex\u0103 de fire musculare despre care se crede c\u0103 sunt r\u0103m\u0103\u0219i\u021be ale dezvolt\u0103rii embrionare&#8221;<\/em>, explic\u0103 cercet\u0103torii \u00eentr-o lucrare publicat\u0103 \u00een revista <strong><em>&#8222;Nature&#8221;<\/em><\/strong> \u00een anul 2020. <em>&#8222;Func\u021bia acestor trabecule la adul\u021bi \u0219i arhitectura lor genetic\u0103 sunt necunoscute. Aici investig\u0103m trabeculele folosind analiza fractal\u0103 la 18.096 de participan\u021bi de la UK Biobank&#8221;.<\/em><\/p>\n<p>Leonardo a desenat trabeculele fine, dantelate, asem\u0103n\u0103toare fulgilor de z\u0103pad\u0103, dup\u0103 ce a examinat \u00eendeaproape o inim\u0103 \u0219i a disecat-o. Artistul a observat probabil structura ramificat\u0103 asem\u0103n\u0103toare r\u0103d\u0103cinii unui copac \u0219i a emis teoria c\u0103 trabeculele erau similare sistemelor pe care le folosim acum pentru a \u00eempiedica \u00eenghe\u021barea trotuarelor \u0219i a drumurilor: o re\u021bea de s\u00e2nge, \u00een acest caz, care era men\u021binut cald prin circula\u021bia \u00een vase mici \u00een jurul inimii calde \u0219i vibrante. Studiind trabeculele, oamenii de \u0219tiin\u021b\u0103 au reu\u0219it s\u0103 identifice caracteristici comune \u00een diferite imagini ale pacien\u021bilor \u0219i s\u0103 \u00eenceap\u0103 s\u0103 trag\u0103 concluzii despre ce fac trabeculele structurale.<\/p>\n<p><em>&#8222;Folosind simul\u0103ri biomecanice \u0219i date observa\u021bionale de la participan\u021bi umani, demonstr\u0103m c\u0103 morfologia trabecular\u0103 este un factor determinant important al performan\u021bei cardiace&#8221;<\/em>, ceea ce \u00eenseamn\u0103 c\u0103 anumite structuri trabeculare au implicat un risc crescut de boli cardiovasculare. <em>&#8222;Am identificat 16 locuri semnificative care con\u021bin gene asociate cu fenotipuri hemodinamice \u0219i reglarea arboriz\u0103rii citoscheletale&#8221;<\/em>, explic\u0103 cercet\u0103torii. Studiind genomul, precum \u0219i trabeculele zecilor de mii de subiec\u021bi, oamenii de \u015ftiin\u0163\u0103 au \u00eenceput s\u0103 identifice locuri din genom care indicau modul \u00een care trabeculele sunt capabile s\u0103 se formeze \u0219i s\u0103 func\u021bioneze &#8211; cu implica\u021bii asupra modului \u00een care se formeaz\u0103 \u0219i se comport\u0103 \u0219i alte celule ale corpului.<\/p>\n<p><em>&#8222;Doar combina\u021bia dintre genetic\u0103, cercetare clinic\u0103 \u0219i bioinginerie ne-a condus la descoperirea rolului nea\u0219teptat al trabeculelor miocardice \u00een func\u021bia inimii adulte&#8221;<\/em>, a declarat cercet\u0103toarea <strong>Hannah Meyer<\/strong>. Cercet\u0103torii spun c\u0103 acesta este doar un prim pas c\u0103tre o \u00een\u021belegere mai complex\u0103 a trabeculelor.<\/p>\n<p><strong>Sursa:<\/strong> studiul \u015ftiin\u0163ific <a href=\"https:\/\/www.nature.com\/articles\/s41586-020-2635-8\" target=\"_blank\" rel=\"noopener\"><strong>&#8222;Genetic and functional insights into the fractal structure of the heart&#8221; \/ nature.com<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dup\u0103 500 de ani, cercet\u0103torii au \u00een\u021beles \u00een sf\u00e2r\u0219it func\u021bia anatomic\u0103 a unei caracteristici a inimii descrise pentru prima dat\u0103 de Leonardo da Vinci. Pentru a g\u0103si r\u0103spunsul, oamenii de \u0219tiin\u021b\u0103 au folosit teoria fractal\u0103, RMN-urile \u0219i mult efort computa\u021bional &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"500 de ani mai t\u00e2rziu, oamenii de \u0219tiin\u021b\u0103 rezolv\u0103 misterul inimii umane, desenat\u0103 de Leonardo da Vinci\" class=\"read-more button\" href=\"https:\/\/www.lovendal.ro\/wp52\/500-de-ani-mai-tarziu-oamenii-de-stiinta-rezolva-misterul-inimii-umane-desenata-de-leonardo-da-vinci\/#more-99320\" aria-label=\"Cite\u0219te mai multe despre 500 de ani mai t\u00e2rziu, oamenii de \u0219tiin\u021b\u0103 rezolv\u0103 misterul inimii umane, desenat\u0103 de Leonardo da Vinci\">Cititi mai multe<\/a><\/p>\n","protected":false},"author":1,"featured_media":99321,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[145,12157,334,225,9794,2364,6324,20138],"class_list":["post-99320","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina","tag-boli","tag-fractali","tag-inima","tag-leonardo-da-vinci","tag-medicina","tag-revista","tag-rmn","tag-trabecule","resize-featured-image"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.3 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>500 de ani mai t\u00e2rziu, oamenii de \u0219tiin\u021b\u0103 rezolv\u0103 misterul inimii umane, desenat\u0103 de Leonardo da Vinci - Secretele lui Lovendal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.lovendal.ro\/wp52\/500-de-ani-mai-tarziu-oamenii-de-stiinta-rezolva-misterul-inimii-umane-desenata-de-leonardo-da-vinci\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"500 de ani mai t\u00e2rziu, oamenii de \u0219tiin\u021b\u0103 rezolv\u0103 misterul inimii umane, desenat\u0103 de Leonardo da Vinci\" \/>\n<meta property=\"og:description\" content=\"Dup\u0103 500 de ani, cercet\u0103torii au \u00een\u021beles \u00een sf\u00e2r\u0219it func\u021bia anatomic\u0103 a unei caracteristici a inimii descrise pentru prima dat\u0103 de Leonardo da Vinci. 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