{"id":93935,"date":"2024-09-26T13:39:24","date_gmt":"2024-09-26T10:39:24","guid":{"rendered":"https:\/\/www.lovendal.ro\/wp52\/?p=93935"},"modified":"2024-09-26T13:39:24","modified_gmt":"2024-09-26T10:39:24","slug":"cercetatorii-au-gasit-in-corpurile-noastre-entitati-ciudate-numite-obeliscuri-functia-lor-ramane-un-mister","status":"publish","type":"post","link":"https:\/\/www.lovendal.ro\/wp52\/cercetatorii-au-gasit-in-corpurile-noastre-entitati-ciudate-numite-obeliscuri-functia-lor-ramane-un-mister\/","title":{"rendered":"Cercet\u0103torii au g\u0103sit \u00een corpurile noastre entit\u0103\u0163i ciudate numite &#8222;obeliscuri&#8221;. Func\u0163ia lor r\u0103m\u00e2ne un mister"},"content":{"rendered":"<p><a href=\"https:\/\/www.lovendal.ro\/wp52\/wp-content\/uploads\/2024\/09\/obeliscuri.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft  wp-image-93936\" src=\"https:\/\/www.lovendal.ro\/wp52\/wp-content\/uploads\/2024\/09\/obeliscuri.jpg\" alt=\"\" width=\"347\" height=\"251\" srcset=\"https:\/\/www.lovendal.ro\/wp52\/wp-content\/uploads\/2024\/09\/obeliscuri.jpg 542w, https:\/\/www.lovendal.ro\/wp52\/wp-content\/uploads\/2024\/09\/obeliscuri-300x217.jpg 300w\" sizes=\"auto, (max-width: 347px) 100vw, 347px\" \/><\/a>Oamenii de \u0219tiin\u021b\u0103 au descoperit entit\u0103\u021bi ciudate care se ascund \u00een intestinele \u0219i gura noastr\u0103 \u015fi care ar putea reprezenta o clas\u0103 complet nou\u0103 de via\u021b\u0103. Denumite <strong>&#8222;obeliscuri&#8221;<\/strong>, aceste inele minuscule de ARN se pot plia \u00eentr-o structur\u0103 care arat\u0103 mai mult ca o tij\u0103, de unde \u0219i numele. Ele sunt, de asemenea, surprinz\u0103tor de obi\u0219nuite \u00een microbiomii no\u0219tri &#8211; comunitatea de viru\u0219i, bacterii, ciuperci \u0219i genele lor care tr\u0103iesc \u00een corpurile noastre. Cu toate acestea, ei au r\u0103mas nedetecta\u021bi p\u00e2n\u0103 acum \u0219i reprezint\u0103 cea mai recent\u0103 descoperire dintr-o list\u0103 \u00een continu\u0103 cre\u0219tere de &#8222;agen\u021bi genetici&#8221; misterio\u0219i care se ascund la vedere. \u00centr-adev\u0103r, cercet\u0103torii care le-au descoperit raporteaz\u0103 c\u0103 func\u021bia lor, dac\u0103 au una, reprezint\u0103 un mister.<\/p>\n<p>Obeliscurile au fost descoperite de o echip\u0103 condus\u0103 de geneticianul \u0219i patologul laureat al Premiului Nobel, <strong>Andrew Fire<\/strong>, care \u0219i-a \u00eemp\u0103rt\u0103\u0219it descoperirile \u00eentr-un studiu \u015ftiin\u0163ific. Folosind un filtru de c\u0103utare a genomului pe care l-au dezvoltat, cercet\u0103torii au descoperit doar 30.000 de obeliscuri, cercet\u00e2nd baza de date <strong>Integrative Human Microbiome Project<\/strong>, un set de date de microbiomi folosit de cercet\u0103torii din \u00eentreaga lume pentru a studia s\u0103n\u0103tatea uman\u0103 \u0219i bolile. C\u00e2nd au c\u0103utat \u00een alte seturi de date despre microbiom din \u00eentreaga lume, au descoperit \u0219i mai multe. \u00centr-un set de date, 6,6% din probele intestinale \u0219i 53% din probele bucale au con\u021binut obeliscuri. <em>&#8222;Prevalen\u021ba \u0219i noutatea aparent\u0103 a acestor elemente implic\u0103 \u00eenc\u0103 mai multe lucruri de aflat despre interac\u021biunea lor cu via\u021ba microbian\u0103 \u0219i uman\u0103&#8221;<\/em>, scriu autorii.<\/p>\n<p>Obeliscurile reprezint\u0103 propria lor clas\u0103 de organisme (dac\u0103 le pute\u021bi numi chiar a\u0219a &#8211; lucrarea se refer\u0103 la ele ca <em>&#8222;entit\u0103\u021bi biologice&#8221;<\/em>). Ele se afl\u0103 undeva \u00eentre viru\u0219i \u0219i viroizi \u2013 ARN circular monocatenar despre care se credea c\u0103 infecteaz\u0103 \u00een principal plantele. De\u0219i arat\u0103 destul de asem\u0103n\u0103tor, viroizii nu pot produce propriile proteine, \u00een timp ce cercet\u0103torii au descoperit c\u0103 obeliscurile pot face acest lucru. Viru\u0219ii, de asemenea, \u00ee\u0219i pot produce propriile proteine, dar au un \u00eenveli\u0219 protector care \u00eenconjoar\u0103 materialul lor genetic, spre deosebire de obeliscuri. Prin urmare, obeliscurile au nevoie de un fel de gazd\u0103. Cercet\u0103torii au reu\u0219it s\u0103 identifice una: o bacterie numit\u0103 <em>Streptococcus sanguinis<\/em> care tr\u0103ie\u0219te mai ales \u00een placa dentar\u0103 din gura noastr\u0103.<\/p>\n<p>\u00cen ultimii ani, oamenii de \u0219tiin\u021b\u0103 au descoperit zeci de mii de noi entit\u0103\u021bi asem\u0103n\u0103toare viroizilor. Este \u00eenc\u0103 discutabil dac\u0103 viru\u0219ii sunt vii, dar\u0103mite ceva mai mic \u0219i mai simplu. <em>&#8222;Este o nebunie&#8221;<\/em>, a declarat Mark Peifer, biolog de celule \u0219i dezvoltare la Universitatea din Carolina de Nord. <em>&#8222;Cu c\u00e2t ne uit\u0103m mai mult, cu at\u00e2t vedem mai multe lucruri nebune\u0219ti&#8221;. <\/em><\/p>\n<p><strong>Sursa:<\/strong> articolul \u015ftiin\u0163ific (preprint) <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.01.20.576352v1.full\" target=\"_blank\" rel=\"noopener\"><strong>&#8222;Viroid-like colonists of human microbiomes&#8221; \/ biorxiv.org<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Oamenii de \u0219tiin\u021b\u0103 au descoperit entit\u0103\u021bi ciudate care se ascund \u00een intestinele \u0219i gura noastr\u0103 \u015fi care ar putea reprezenta o clas\u0103 complet nou\u0103 de via\u021b\u0103. Denumite &#8222;obeliscuri&#8221;, aceste inele minuscule de ARN se pot plia \u00eentr-o structur\u0103 care arat\u0103 &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Cercet\u0103torii au g\u0103sit \u00een corpurile noastre entit\u0103\u0163i ciudate numite &#8222;obeliscuri&#8221;. Func\u0163ia lor r\u0103m\u00e2ne un mister\" class=\"read-more button\" href=\"https:\/\/www.lovendal.ro\/wp52\/cercetatorii-au-gasit-in-corpurile-noastre-entitati-ciudate-numite-obeliscuri-functia-lor-ramane-un-mister\/#more-93935\" aria-label=\"Cite\u0219te mai multe despre Cercet\u0103torii au g\u0103sit \u00een corpurile noastre entit\u0103\u0163i ciudate numite &#8222;obeliscuri&#8221;. Func\u0163ia lor r\u0103m\u00e2ne un mister\">Cititi mai multe<\/a><\/p>\n","protected":false},"author":1,"featured_media":93936,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[3723,9706,145,9070,1464,3711,5941,7199,4001,19315,11283,9794,19313,6045,309,186,2250,366,19314,5841],"class_list":["post-93935","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina","tag-arn","tag-bacterii","tag-boli","tag-carolina-de-nord","tag-ciuperci","tag-gene","tag-genetician","tag-genom","tag-gura","tag-integrative-human-microbiome-project","tag-intestine","tag-medicina","tag-obeliscuri","tag-plante","tag-premiul-nobel","tag-proteine","tag-universitate","tag-viata","tag-viroizi","tag-virusi","resize-featured-image"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.3 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cercet\u0103torii au g\u0103sit \u00een corpurile noastre entit\u0103\u0163i ciudate numite &quot;obeliscuri&quot;. 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Func\u0163ia lor r\u0103m\u00e2ne un mister - Secretele lui Lovendal","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.lovendal.ro\/wp52\/cercetatorii-au-gasit-in-corpurile-noastre-entitati-ciudate-numite-obeliscuri-functia-lor-ramane-un-mister\/","og_locale":"ro_RO","og_type":"article","og_title":"Cercet\u0103torii au g\u0103sit \u00een corpurile noastre entit\u0103\u0163i ciudate numite \"obeliscuri\". Func\u0163ia lor r\u0103m\u00e2ne un mister","og_description":"Oamenii de \u0219tiin\u021b\u0103 au descoperit entit\u0103\u021bi ciudate care se ascund \u00een intestinele \u0219i gura noastr\u0103 \u015fi care ar putea reprezenta o clas\u0103 complet nou\u0103 de via\u021b\u0103. Denumite &#8222;obeliscuri&#8221;, aceste inele minuscule de ARN se pot plia \u00eentr-o structur\u0103 care arat\u0103 ... 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