{"id":100162,"date":"2025-10-01T11:30:22","date_gmt":"2025-10-01T08:30:22","guid":{"rendered":"https:\/\/www.lovendal.ro\/wp52\/?p=100162"},"modified":"2025-10-01T11:31:08","modified_gmt":"2025-10-01T08:31:08","slug":"oamenii-ar-putea-avea-un-al-treilea-set-de-dinti-ascuns-iar-japonezii-au-descoperit-cum-sa-i-activeze","status":"publish","type":"post","link":"https:\/\/www.lovendal.ro\/wp52\/oamenii-ar-putea-avea-un-al-treilea-set-de-dinti-ascuns-iar-japonezii-au-descoperit-cum-sa-i-activeze\/","title":{"rendered":"Oamenii ar putea avea ascuns un al treilea set de din\u021bi, iar japonezii au descoperit cum s\u0103-i activeze"},"content":{"rendered":"

\"\"<\/a>Un studiu realizat \u00een Japonia<\/em> a ar\u0103tat cum direc\u021bionarea genelor poate regenera din\u021bii la animale. Acum, echipa de cercet\u0103tori apeleaz\u0103 la un studiu clinic pe oameni. Prin vizarea genei USAG-1<\/strong>, cercet\u0103torii cred c\u0103 pot ajuta persoanele f\u0103r\u0103 o denti\u0163ie complet\u0103 s\u0103 \u00ee\u0219i regenereze din\u021bii. Echipa spune c\u0103 oamenii au un al treilea set de din\u021bi disponibili sub form\u0103 de muguri, gata s\u0103 creasc\u0103 dup\u0103 cum este necesar.<\/p>\n

Cum a \u00eenceput totul? \u00cen urma unui studiu din 2021, care a ar\u0103tat cum medicamentele care vizeaz\u0103 proteina sintetizat\u0103 de gena USAG-1 ar putea influen\u021ba num\u0103rul de din\u021bi crescu\u021bi la animale, echipa \u0219i-a \u00eendreptat aten\u021bia c\u0103tre oameni. Ace\u0219tia au anun\u021bat un studiu clinic pe oameni, pe care sper\u0103 s\u0103 \u00eel aib\u0103 gata de utilizare general\u0103 \u00een 2030.<\/p>\n

„Ideea de a cre\u0219te din\u021bi noi este visul oric\u0103rui dentist. Lucrez la asta \u00eenc\u0103 de c\u00e2nd eram student la masterat. Eram \u00eencrez\u0103tor c\u0103 voi putea s\u0103 o realizez”<\/em>, a declarat Katsu Takahashi<\/strong>, cercet\u0103tor principal \u0219i \u0219eful departamentului de stomatologie \u0219i chirurgie oral\u0103 de la Institutul de Cercet\u0103ri Medicale Kitano din Osaka. „Sper\u0103m s\u0103 vedem un moment \u00een care medicina pentru regenerarea din\u021bilor va fi o a treia op\u021biune al\u0103turi de proteze dentare \u0219i implanturi”.<\/em><\/p>\n

Takahashi a petrecut ani de zile cercet\u00e2nd poten\u021bialul de regenerare a din\u021bilor \u0219i s-a concentrat pe rolul genelor \u00een acest proces. „Num\u0103rul de din\u021bi a variat prin muta\u021bia unei singure gene”<\/em>, a spus el. „Dac\u0103 facem din acesta obiectivul cercet\u0103rii noastre, ar trebui s\u0103 existe o modalitate de a schimba num\u0103rul de din\u021bi (pe care \u00eei au oamenii)”<\/em>.<\/p>\n

Cercet\u0103torii au descoperit c\u0103 proteina USAG-1 ar putea limita cre\u0219terea din\u021bilor la \u0219oareci; deci, dac\u0103 proteina nu se formeaz\u0103, ar putea stimula cre\u0219terea din\u021bilor. Echipa a dezvoltat un medicament pentru a bloca proteina \u0219i a permis cu succes \u0219oarecilor s\u0103 le dezvolte din\u021bi noi.<\/p>\n

O lucrare din 2023 publicat\u0103 \u00een „Regenerative Therapy”<\/em><\/strong> denun\u021b\u0103 lipsa tratamentelor disponibile pentru regenerarea din\u021bilor, dar subliniaz\u0103 modul \u00een care tratamentul cu anticorpi anti-USAG-1 la \u0219oareci ar putea oferi o descoperire \u00een tratarea anomaliilor dentare la oameni. Av\u00e2nd \u00een vedere c\u0103 aproximativ 1% dintre oameni sufer\u0103 de anodon\u0163ie<\/em>, o afec\u021biune genetic\u0103 ce nu permite cre\u0219terea complet\u0103 a din\u021bilor, exist\u0103 speran\u021b\u0103 pentru regenerarea din\u021bilor la oameni dincolo de studiile clinice efectuate pe \u0219oareci.<\/p>\n

Takahashi a spus c\u0103 cercet\u0103rile sale anterioare arat\u0103 c\u0103 oamenii au deja \u00eenceputul unui al treilea set de din\u021bi \u00eencorporat \u00een gur\u0103. Acest lucru este cel mai vizibil manifestat de 1% dintre oameni cu hiperdon\u021bie<\/em>, cre\u0219terea a mai mult dec\u00e2t un set complet de din\u021bi. Iar Takahashi consider\u0103 c\u0103 activarea acelui al treilea set de muguri prin manipularea genetic\u0103 corect\u0103 ar putea promova regenerarea din\u021bilor. Dac\u0103 totul merge bine \u00een studiul clinic, lumea ar putea avea mai mul\u021bi din\u021bi \u00eenc\u0103 din 2030.<\/p>\n

Surse:<\/strong>
\n– Articolul „World’s 1st ‘tooth regrowth’ medicine moves toward clinical trials in Japan” \/ mainichi.jp<\/strong><\/a>
\n– Studiul \u015ftiin\u0163ific „Advances in tooth agenesis and tooth regeneration” \/ sciencedirect.com<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Un studiu realizat \u00een Japonia a ar\u0103tat cum direc\u021bionarea genelor poate regenera din\u021bii la animale. Acum, echipa de cercet\u0103tori apeleaz\u0103 la un studiu clinic pe oameni. Prin vizarea genei USAG-1, cercet\u0103torii cred c\u0103 pot ajuta persoanele f\u0103r\u0103 o denti\u0163ie complet\u0103 … <\/p>\n

Cititi mai multe<\/a><\/p>\n","protected":false},"author":1,"featured_media":100163,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[1542,3711,9787,128,4999,9794,57,13570,186,351],"class_list":["post-100162","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicina","tag-dinti","tag-gene","tag-japonezi","tag-japonia","tag-medicamente","tag-medicina","tag-oameni","tag-osaka","tag-proteine","tag-soareci","resize-featured-image"],"yoast_head":"\nOamenii ar putea avea ascuns un al treilea set de din\u021bi, iar japonezii au descoperit cum s\u0103-i activeze - Secretele lui Lovendal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.lovendal.ro\/wp52\/oamenii-ar-putea-avea-un-al-treilea-set-de-dinti-ascuns-iar-japonezii-au-descoperit-cum-sa-i-activeze\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Oamenii ar putea avea ascuns un al treilea set de din\u021bi, iar japonezii au descoperit cum s\u0103-i activeze\" \/>\n<meta property=\"og:description\" content=\"Un studiu realizat \u00een Japonia a ar\u0103tat cum direc\u021bionarea genelor poate regenera din\u021bii la animale. 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